Adriana Dinescu
Assistant Professor of Chemistry

Wilkes University
84 W South St
Wilkes Barre, PA 18766

Office: CSC 408
Phone: (570) 408-4623
adriana.dinescu_at_wilkes.edu

 

"A teacher is never a giver of truth - he is a guide, a pointer to the truth that each student must find for himself. A good teacher is merely a catalyst". Bruce Lee

 

CHM 113, Fall 2015 (all lab sections)

 

Work Experience

08/09 – present           Assistant Professor of Chemistry, Wilkes University

08/08 – 08/09             Lecturer, Butler University

03/07 – 08/08             Postdoctoral Research Associate, Idaho National Laboratory

 

Education

08/08          Postdoctoral Research Associate
                  Washington State University - Idaho National Laboratory

05/07          Ph.D. in Chemistry
                  University of North Texas                               

06/93          B.Eng. in Chemistry
                  Polytechnica University of Bucharest, Romania

 

PUBLICATIONS

  1. Teresa R. Brown, Michael L. Drummond, Sarah Barelier, Amanda S. Crutchfield, Adriana Dinescu, Kerri D. Slavens, Thomas R. Cundari, Mary E. Anderson, “Aspartate 458 of human glutathione synthetase is important for cooperativity and active site structure.” Biochem. Biophys. Res. Comm. 2011; 411: 536-542.

  2. Garold L. Gresham, Adriana Dinescu, Michael T. Benson, Michael J. Van Stipdonk, Gary S. Groenewold, “Investigation of Uranyl Nitrate Ion Pairs Complexed with Amide Ligands Using Electrospray Ionization Ion Trap Mass Spectrometry and Density Functional Theory.” J. Phys. Chem. A 2011; 115: 3497-3508.

  3. Adriana Dinescu, Teresa R. Brown, Sarah Barelier, Thomas R. Cundari, Mary E. Anderson, “Role of the glycine triad in human glutathione synthetase.” Biochem. Biophys. Res. Comm. 2010; 400: 511-516.

  4. Timothy E. Machonkin, Patrick L. Holland, Kristine N. Smith, Justin S. Liberman, Adriana Dinescu, Thomas R. Cundari, Sara S. Rocks, “Determination of the active site of Sphingobium chlorophenolicum 2,6-dichlorohydroquinone dioxygenase (PcpA).” J. Biol. Inorg. Chem. 2010; 15: 291-301.

  5. Yosra M. Badiei, Adriana Dinescu, Xuliang Dai, Robert M. Palomino, Frank Heinemann, Thomas R. Cundari, Timothy H. Warren, “Copper Nitrenes in Catalytic C-H Amination.” Angew. Chem. Int. Ed. 2008; 47: 9961-9964.

  6. Adriana Dinescu, Michael T. Benson, “Electronic Structure Studies on Deprotonation of Dithiophosphinic Acids in Water Clusters.” J. Phys. Chem. A 2008; 112: 12270-12280.

  7. Thomas R. Cundari, Adriana Dinescu, Abul B. Kazi, “Bonding and Structure of Copper-Nitrenes.” Inorg. Chem. 2008; 47: 10067-10072.

  8. Adriana Dinescu, Aurora E. Clark, “Thermodynamic and Structural Features of Aqueous Ce(III).” J. Phys. Chem. A 2008; 112: 11198-11206.

  9. Michael T. Benson, Megan L. Moser, Dean R. Peterman, Adriana Dinescu, “Determination of pKa for Dithiophosphinic Acids Using Density Functional Theory.” J. Mol. Struct. THEOCHEM 2008; 867: 71-77.

  10. Thomas R. Cundari, Adriana Dinescu, Dunming Zhu, and Ling Hua, “A molecular modeling study on the enantioselectivity of aryl alkyl ketone reductions by a NADPH-dependent carbonyl reductase.” J. Mol. Model. 2007; 13: 685-690.

  11. Abul B. Kazi, Thomas R. Cundari, Eduard Baba, Nathan J. DeYonker, Adriana Dinescu, and Lloyd Spaine, “Catalytic Synthesis of Arylisocyanates from Nitroaromatics. A Computational Study.”Organometallics 2007; 26: 910-914.

  12. Adriana Dinescu, Mary E. Anderson, and Thomas R. Cundari, “Catalytic Loop Motion in Human Glutathione Synthetase: A Molecular Modeling Approach.” Biochem. Biophys. Res. Comm. 2007; 353: 450-456.

  13. Nathan J. DeYonker, Tom Grimes, Scott Yockel, Adriana Dinescu, Benjamin J. Mintz, Thomas R. Cundari, and Angela K. Wilson, “The correlation-consistent composite approach: Application to the G3/99 test set.” J. Chem. Phys. 2006; 125: 104111/1-15.

  14. Adriana Dinescu, Clinton E. Whiteley, Rachel R. Combs, and Thomas R. Cundari, “Oxygen Atom Transfer Energetics: Assessment of the Effect of Method and Solvent.” J. Phys. Chem. A 2006; 110: 4053-4056.

  15. Orson L. Sydora, David S. Kuiper, Peter T. Wolczanski, Emil B. Lobkovsky, Adriana Dinescu, and Thomas R. Cundari, “The Butterfly Dimer [(tBu3SiO)Cr]2(μ-OSitBu3)2 and its Oxidative Cleavage to (tBu3SiO)2Cr(=N-N=CPh2)2 and (tBu3SiO)2Cr=N(2,6-Ph2-C6H3).” Inorg. Chem. 2006; 45: 2008-2021.

  16. Nathan A. Eckert, Adriana Dinescu, Thomas R. Cundari, and Patrick L. Holland, “A T-Shaped Three-Coordinate Nickel(I) Carbonyl Complex and the Geometric Preferences of Three-Coordinate d9 Complexes.” Inorg. Chem. 2005; 44: 7702 –7704.

  17. Corneliu Buda,  Abul B. Kazi, Adriana Dinescu, and Thomas R. Cundari, “Stability Studies of Transition-Metal Linkage Isomers Using Quantum Mechanical Methods. Groups 11 and 12 Transition Metals.” J. Chem. Inf. Modeling 2005; 45: 965-970.

  18. Adriana Dinescu, Thomas R. Cundari, Vikas S. Bhansali, Jia-Li Luo, and Mary E. Anderson, “Function of Conserved Residues of Human Glutathione Synthetase: Implications for the ATP-grasp Enzymes.” J. Biol. Chem. 2004; 279: 22412 – 22421.

RESEARCH GRANTS

  1. ACS Petroleum Research Fund, PRF # 51903-UNI3, $50,000 Title: Biomimetic Catalysts for Hydrogen Production and Carbon Dioxide Activation (awarded in October 2011).

  2. NSF through TeraGrid resources TG-CHE110036 – 100,000 hours of CPU-time provided by Pittsburgh Supercomputing Center. Title: Laboratory Experiences in Computational Chemistry for Undergraduates (awarded in January 2011 and renewed in 2012, 2013, 2014 and 2015).

  3. Faculty Development Grant (Type I), Wilkes University - $4,017.75 Title: Biomimetic Models and Analogs of Carbon Monoxide Dehydrogenase Active Site (awarded in April 2011).

  4. Mentoring Project Fund, Wilkes University - $4,248.00. Title: Research Experiences for Undergraduates in Computational Chemistry (awarded in May 2011).

  5. Mentoring Project Fund, Wilkes University - $4,730.00. Title: Copper-Molybdenum Interaction in Carbon Monoxide Dehydrogenase (awarded in May 2010).

  6. NSF through TeraGrid resources TG-CHE100051 – 30,000 hours of CPU-time provided by Pittsburgh Supercomputing Center. Title: Modeling the Active Site of Carbon Monoxide Dehydrogenase for Hydrogen Production (awarded in March 2010).

 

AWARDS

  • 2007 Graduate Council Dissertation Award for Research Achievement in the Natural Sciences and Mathematics, Robert B. Toulouse School of Graduate Studies, University of North Texas

  • 2007 James J. and Ruth I. Spurlock Scholarship Award for Outstanding Research Achievement by a Graduate Student in the Chemistry Department, University of North Texas

  • 2006 College of Arts and Sciences Summer Scholarship, University of North Texas

  • 2006 Graduate Student Travel Grant, Robert B. Toulouse School of Graduate Studies, University of North Texas

  • 2006 B. Craig Raupe Memorial Scholarship, Student Government Association, University of North Texas

  • 2005 ASBMB Graduate Travel Award, American Society for Biochemistry and Molecular Biology

  • 2004 Academic Achievement Scholarship, Robert B. Toulouse School of Graduate Studies, University of North Texas

  • 2004 George Vaughan Memorial Award for outstanding first or second year graduate student in the Chemistry Department, University of North Texas

  • 2004 ASBMB Graduate Travel Award, American Society for Biochemistry and Molecular Biology

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